Zinc deficiency
Updated . Vsevolod Dobrovolskyi
Zinc is needed for immunity, wound healing, taste and smell. Clear zinc deficiency is uncommon in people with a varied diet. It is usually linked to bowel conditions, alcohol or a very restricted diet.
Symptoms
Most signs are non-specific:
- food tastes bland or “off”, a dulled sense of smell;
- cuts and scrapes heal slowly;
- a red, scaly rash around the mouth, nose, eyes, hands or feet;
- hair loss.
Changes in taste and smell often follow a cold or COVID-19, and zinc has nothing to do with them.
Who is at risk
- coeliac disease, Crohn’s disease, chronic diarrhoea, bowel surgery;
- heavy alcohol use;
- a vegetarian diet (zinc from plants is less well absorbed);
- very restrictive eating;
- liver or kidney disease;
- diuretics;
- pregnancy and breastfeeding.
Which test to ask for
Plasma or serum zinc, but usually only when a doctor suspects deficiency for other reasons.
The test is unreliable: the result shifts after meals, through the day, with inflammation and with low albumin. A normal number does not rule out deficiency, and a low one does not always mean it.
What not to do
Do not take zinc long-term without a reason. Excess zinc causes copper deficiency, which leads to anaemia and nerve damage resembling B12 deficiency.
Sources
- NIH ODS — Zinc, Fact Sheet for Health Professionals
- MSD Manual — Zinc Deficiency
- King et al. — Biomarkers of Nutrition for Development, Zinc Review (2015)
Checked against published sources; not yet reviewed by a clinician.